Technical Leader, Vaccine Stabilization

Technical Leader, Vaccine Stabilization

Location: Seattle, Washington

Starting Annual Salary Range: Commensurate with experience

Program Objective:

The Vaccine Stabilization team, under the Technology Solutions Strategic Program at PATH, conducts collaborative research and development with vaccine producers and stabilization technology companies in pursuit of thermostable vaccines appropriate for use in public-sector, developing-country immunization programs. Initial efforts focus on stabilization of a few priority vaccines (e.g., hepatitis B, Hib, DPT, and combinations of these vaccines, as well as measles vaccine). Vaccine candidates will be added or revised as the project progresses.

Duties and Responsibilities:

The Technical Leader will oversee and coordinate all technical, regulatory, pre-clinical, and clinical project activities on behalf of PATH. Work will be conducted off-site and will involve vaccine producers, stabilization technology companies, suppliers, contract formulation and fill facilities, and laboratories. Emphasis may be given to working with vaccine producers in developing or emerging countries. Consultants and staff members will assist the Technical Leader in these activities.

The Technical Leader will work closely with the overall Project Leader and other core team members, including business development, administrative, procurement, field, and technical staff. Specific project activities will be defined, modified, and budgeted within this team-based structure to ensure maximum yield for the donors’ investment within a minimal time frame and to reflect the priorities and needs of developing-country immunization programs. Other project activities, such as intellectual property evaluation/management and economic analyses, will complement the technical components of this project.

Specific duties and responsibilities include:

  • Assume technical leadership and responsibility within the project team for ongoing and new technical activities with collaborators, including the stabilization, testing, clinical evaluation, and scale-up of priority vaccines. Ensure that all applicable regulatory and other requirements are met.
  • Evaluate promising new stabilization and administration formats, as appropriate.
  • Identify, hire, and monitor consultants and contract facilities to conduct technical work supported directly through PATH. Provide technical advice to collaborators.
  • Ensure scientific and technical credibility for project activities. Obtain objective review of specific activities and plans through meetings with consultants and internal and external advisors.
  • Work with partners, staff, and consultants to evaluate and ensure the feasibility of production scale-up for promising thermostable vaccines.
  • Assist the Project Leader with overall strategy development.
  • Present data at scientific and other meetings, as appropriate.
  • Responsible to the Project Leader for achieving technical project goals and objectives within the allocated budgets and timeframes.

Qualifications:

  • Advanced degree (MD, Ph.D., or Masters) required.
  • Minimum 10 years work experience including 8 years industry experience in the field of vaccine formulation and development required with expertise in preclinical testing and preparation of product for clinical trials; preferably in an FDA regulated environment.
  • Direct work with stabilization methodologies, particularly use of sugar and composite glasses, and technology transfer highly desirable.
  • Knowledge of vaccine manufacturing, including spray drying and lyophilization, highly desirable.
  • Familiarity with international health organizations (e.g., WHO, UNICEF) structures highly desirable.
  • Demonstrated leadership and management skills, preferably in the field of vaccine or drug development.
  • Demonstrated ability to work with multiple partners in a collaborative setting.
  • Demonstrated ability to work in an interdisciplinary, team-based organizational structure.
  • Experience working in a project-milestone framework.
  • Fluency in English.
  • International and domestic travel by air is required—up to 30% annually.

To Apply:

To be considered for this position, please visit our website, http://www.path.org, and click on "Job Opportunities." Please carefully read and follow the instructions at the bottom of the job description to ensure that all required documents are submitted appropriately.

All posted positions are full time unless otherwise noted.

PATH is dedicated to diversity in staff and is an equal opportunity employer.

PATH
Reference Job Code: 1398

PATH is an Equal Opportunity Employer